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Systematic Approaches towards the Development of Host-Directed Antiviral Therapeutics

Since the onset of antiviral therapy, viral resistance has compromised the clinical value of small-molecule drugs targeting pathogen components. As intracellular parasites, viruses complete their life cycle by hijacking a multitude of host-factors. Aiming at the latter rather than the pathogen direc...

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Detalles Bibliográficos
Autores principales: Prussia, Andrew, Thepchatri, Pahk, Snyder, James P., Plemper, Richard K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131607/
https://www.ncbi.nlm.nih.gov/pubmed/21747723
http://dx.doi.org/10.3390/ijms12064027