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Ellipticine cytotoxicity to cancer cell lines — a comparative study

Ellipticine is a potent antineoplastic agent exhibiting multiple mechanisms of action. This anticancer agent should be considered a pro-drug, whose pharmacological efficiency and/or genotoxic side effects are dependent on its cytochrome P450 (CYP)- and/or peroxidase-mediated activation to species fo...

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Detalles Bibliográficos
Autores principales: Stiborová, Marie, Poljaková, Jitka, Martínková, Eva, Bořek-Dohalská, Lucie, Eckschlager, Tomáš, Kizek, Rene, Frei, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Slovak Toxicology Society SETOX 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131681/
https://www.ncbi.nlm.nih.gov/pubmed/21753906
http://dx.doi.org/10.2478/v10102-011-0017-7