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The tumour-associated glycoprotein podoplanin is expressed in fibroblast-like synoviocytes of the hyperplastic synovial lining layer in rheumatoid arthritis

INTRODUCTION: Activated fibroblast-like synoviocytes (FLSs) in rheumatoid arthritis (RA) share many characteristics with tumour cells and are key mediators of synovial tissue transformation and joint destruction. The glycoprotein podoplanin is upregulated in the invasive front of several human cance...

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Detalles Bibliográficos
Autores principales: Ekwall, Anna-Karin H, Eisler, Thomas, Anderberg, Christian, Jin, Chunsheng, Karlsson, Niclas, Brisslert, Mikael, Bokarewa, Maria I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132020/
https://www.ncbi.nlm.nih.gov/pubmed/21385358
http://dx.doi.org/10.1186/ar3274