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Chromatin as a target antigen in human and murine lupus nephritis

The present review focuses on pathogenic molecular and transcriptional events in patients with lupus nephritis. These factors are renal DNaseI, exposed chromatin fragments and the corresponding chromatin-reactive autoantibodies. Lupus nephritis is the most serious complication in human systemic lupu...

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Detalles Bibliográficos
Autores principales: Hedberg, Annica, Mortensen, Elin S, Rekvig, Ole P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132027/
https://www.ncbi.nlm.nih.gov/pubmed/21542875
http://dx.doi.org/10.1186/ar3281