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Chromatin as a target antigen in human and murine lupus nephritis
The present review focuses on pathogenic molecular and transcriptional events in patients with lupus nephritis. These factors are renal DNaseI, exposed chromatin fragments and the corresponding chromatin-reactive autoantibodies. Lupus nephritis is the most serious complication in human systemic lupu...
Autores principales: | Hedberg, Annica, Mortensen, Elin S, Rekvig, Ole P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132027/ https://www.ncbi.nlm.nih.gov/pubmed/21542875 http://dx.doi.org/10.1186/ar3281 |
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