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Anti-T cell immunoglobulin and mucin domain-2 monoclonal antibody exacerbates collagen-induced arthritis by stimulating B cells

INTRODUCTION: T cell immunoglobulin and mucin domain-2 (TIM-2) has been shown to regulate CD4 T cell activation. However, the role of TIM-2 in the autoimmune disease models has not been clarified yet. In this study, we investigated the effects of anti-TIM-2 monoclonal antibodies (mAbs) in collagen-i...

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Detalles Bibliográficos
Autores principales: Kawamoto, Toshio, Abe, Yoshiyuki, Ito, Jun, Makino, Fumihiko, Kojima, Yuko, Usui, Yoshihiko, Ma, Juan, Morimoto, Shinji, Yagita, Hideo, Okumura, Ko, Takasaki, Yoshinari, Akiba, Hisaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132034/
https://www.ncbi.nlm.nih.gov/pubmed/21426565
http://dx.doi.org/10.1186/ar3288