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Diversity and flexibility of Th17 effector functions

IL-17-producing CD4(+ )T-helper cells (Th17 cells) have been recognised as important drivers of pathogenesis in a multitude of inflammatory diseases, including arthritis. The cytokines and transcription factors that instruct and execute Th17 lineage differentiation have been identified. This has ind...

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Detalles Bibliográficos
Autores principales: Kamradt, Thomas, Chang, Hyun-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132042/
https://www.ncbi.nlm.nih.gov/pubmed/21542876
http://dx.doi.org/10.1186/ar3296