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Whole blood transcriptional profiling in ankylosing spondylitis identifies novel candidate genes that might contribute to the inflammatory and tissue-destructive disease aspects

INTRODUCTION: A number of genetic-association studies have identified genes contributing to ankylosing spondylitis (AS) susceptibility but such approaches provide little information as to the gene activity changes occurring during the disease process. Transcriptional profiling generates a 'snap...

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Detalles Bibliográficos
Autores principales: Pimentel-Santos, Fernando M, Ligeiro, Dário, Matos, Mafalda, Mourão, Ana F, Costa, José, Santos, Helena, Barcelos, Anabela, Godinho, Fátima, Pinto, Patricia, Cruz, Margarida, Fonseca, João E, Guedes-Pinto, Henrique, Branco, Jaime C, Brown, Matthew A, Thomas, Gethin P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132052/
https://www.ncbi.nlm.nih.gov/pubmed/21470430
http://dx.doi.org/10.1186/ar3309