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Mannan Binding Lectin (MBL) genotypes coding for high MBL serum levels are associated with rheumatoid factor negative rheumatoid arthritis in never smokers

INTRODUCTION: Previous studies have provided inconsistent results on whether variants in the MBL2 gene, coding for the complement-activating mannan-binding lectin (MBL) protein, associate with rheumatoid arthritis (RA). We re-evaluated this in context of the main environmental and genetic risk facto...

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Detalles Bibliográficos
Autores principales: Saevarsdottir, Saedis, Ding, Bo, Steinsson, Kristjan, Grondal, Gerdur, Valdimarsson, Helgi, Alfredsson, Lars, Klareskog, Lars, Padyukov, Leonid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132060/
https://www.ncbi.nlm.nih.gov/pubmed/21496252
http://dx.doi.org/10.1186/ar3321