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Alpha cells secrete acetylcholine as a non-neuronal paracrine signal priming human beta cell function

Acetylcholine is a neurotransmitter that plays a major role in the function of the insulin secreting pancreatic beta cell(1,2). Parasympathetic innervation of the endocrine pancreas, the islets of Langerhans, has been shown to provide cholinergic input to the beta cell in several species(1,3,4), but...

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Detalles Bibliográficos
Autores principales: Rodriguez-Diaz, Rayner, Dando, Robin, Jacques-Silva, M. Caroline, Fachado, Alberto, Molina, Judith, Abdulreda, Midhat, Ricordi, Camillo, Roper, Stephen D., Berggren, Per-Olof, Caicedo, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132226/
https://www.ncbi.nlm.nih.gov/pubmed/21685896
http://dx.doi.org/10.1038/nm.2371