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Regulation of Circulating Sclerostin Levels by Sex Steroids in Women and in Men

Sex steroids are important regulators of bone turnover, but the mechanisms of their effects on bone remain unclear. Sclerostin is an inhibitor of Wnt signaling, and circulating estrogen (E) levels are inversely associated with sclerostin levels in postmenopausal women. To directly test for sex stero...

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Detalles Bibliográficos
Autores principales: Mödder, Ulrike IL, Clowes, Jackie A, Hoey, Kelley, Peterson, James M, McCready, Louise, Oursler, Merry Jo, Riggs, B Lawrence, Khosla, Sundeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132405/
https://www.ncbi.nlm.nih.gov/pubmed/20499362
http://dx.doi.org/10.1002/jbmr.128