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The GPR55 agonist lysophosphatidylinositol directly activates intermediate-conductance Ca(2+)-activated K(+) channels
Lysophosphatidylinositol (LPI) was recently shown to act both as an extracellular mediator binding to G protein-coupled receptor 55 (GPR55) and as an intracellular messenger directly affecting a number of ion channels including large-conductance Ca(2+) and voltage-gated potassium (BK(Ca)) channels....
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132407/ https://www.ncbi.nlm.nih.gov/pubmed/21603896 http://dx.doi.org/10.1007/s00424-011-0977-7 |