Cargando…
Evolutionary diversity and developmental regulation of X-chromosome inactivation
X-chromosome inactivation (XCI) results in the transcriptional silencing of one X-chromosome in females to attain gene dosage parity between XX female and XY male mammals. Mammals appear to have developed rather diverse strategies to initiate XCI in early development. In placental mammals XCI depend...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132430/ https://www.ncbi.nlm.nih.gov/pubmed/21687993 http://dx.doi.org/10.1007/s00439-011-1029-2 |