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Chromosome-wide DNA methylation analysis predicts human tissue-specific X inactivation

X-chromosome inactivation (XCI) results in the differential marking of the active and inactive X with epigenetic modifications including DNA methylation. Consistent with the previous studies showing that CpG island-containing promoters of genes subject to XCI are approximately 50% methylated in fema...

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Detalles Bibliográficos
Autores principales: Cotton, Allison M., Lam, Lucia, Affleck, Joslynn G., Wilson, Ian M., Peñaherrera, Maria S., McFadden, Deborah E., Kobor, Michael S., Lam, Wan L., Robinson, Wendy P., Brown, Carolyn J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132437/
https://www.ncbi.nlm.nih.gov/pubmed/21597963
http://dx.doi.org/10.1007/s00439-011-1007-8