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Chromosome-wide DNA methylation analysis predicts human tissue-specific X inactivation
X-chromosome inactivation (XCI) results in the differential marking of the active and inactive X with epigenetic modifications including DNA methylation. Consistent with the previous studies showing that CpG island-containing promoters of genes subject to XCI are approximately 50% methylated in fema...
Autores principales: | Cotton, Allison M., Lam, Lucia, Affleck, Joslynn G., Wilson, Ian M., Peñaherrera, Maria S., McFadden, Deborah E., Kobor, Michael S., Lam, Wan L., Robinson, Wendy P., Brown, Carolyn J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132437/ https://www.ncbi.nlm.nih.gov/pubmed/21597963 http://dx.doi.org/10.1007/s00439-011-1007-8 |
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