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Effects of HBV Genetic Variability on RNAi Strategies

RNAi strategies present promising antiviral strategies against HBV. RNAi strategies require base pairing between short RNAi effectors and targets in the HBV pregenome or other RNAs. Natural variation in HBV genotypes, quasispecies variation, or mutations selected by the RNAi strategy could potential...

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Detalles Bibliográficos
Autores principales: Panjaworayan, Nattanan, Brown, Chris M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132485/
https://www.ncbi.nlm.nih.gov/pubmed/21760994
http://dx.doi.org/10.1155/2011/367908