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Tonic Modulation of Spinal Hyperexcitability by the Endocannabinoid Receptor System in a Rat Model of Osteoarthritis Pain

OBJECTIVE: To investigate the impact of an experimental model of osteoarthritis (OA) on spinal nociceptive processing and the role of the inhibitory endocannabinoid system in regulating sensory processing at the spinal level. METHODS: Experimental OA was induced in rats by intraarticular injection o...

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Detalles Bibliográficos
Autores principales: Sagar, Devi Rani, Staniaszek, Lydia E, Okine, Bright N, Woodhams, Stephen, Norris, Leonie M, Pearson, Richard G, Garle, Michael J, Alexander, Stephen P H, Bennett, Andrew J, Barrett, David A, Kendall, David A, Scammell, Brigitte E, Chapman, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132591/
https://www.ncbi.nlm.nih.gov/pubmed/20722027
http://dx.doi.org/10.1002/art.27698