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Tonic Modulation of Spinal Hyperexcitability by the Endocannabinoid Receptor System in a Rat Model of Osteoarthritis Pain
OBJECTIVE: To investigate the impact of an experimental model of osteoarthritis (OA) on spinal nociceptive processing and the role of the inhibitory endocannabinoid system in regulating sensory processing at the spinal level. METHODS: Experimental OA was induced in rats by intraarticular injection o...
Autores principales: | Sagar, Devi Rani, Staniaszek, Lydia E, Okine, Bright N, Woodhams, Stephen, Norris, Leonie M, Pearson, Richard G, Garle, Michael J, Alexander, Stephen P H, Bennett, Andrew J, Barrett, David A, Kendall, David A, Scammell, Brigitte E, Chapman, Victoria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wiley Subscription Services, Inc., A Wiley Company
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132591/ https://www.ncbi.nlm.nih.gov/pubmed/20722027 http://dx.doi.org/10.1002/art.27698 |
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