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α4-Containing GABA(A) Receptors are Required for Antagonism of Ethanol-Induced Motor Incoordination and Hypnosis by the Imidazobenzodiazepine Ro15-4513

Alcohol (ethanol) is widely consumed for its desirable effects but unfortunately has strong addiction potential. Some imidazobenzodiazepines such as Ro15-4513 are able to antagonize many ethanol-induced behaviors. Controversial biochemical and pharmacological evidence suggest that the effects of the...

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Detalles Bibliográficos
Autores principales: Iyer, Sangeetha V., Benavides, Rodrigo A., Chandra, Dev, Cook, James M., Rallapalli, Sundari, June, Harry L., Homanics, Gregg E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132666/
https://www.ncbi.nlm.nih.gov/pubmed/21779248
http://dx.doi.org/10.3389/fphar.2011.00018