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Bacterial Carbonic Anhydrases as Drug Targets: Toward Novel Antibiotics?
Carbonic anhydrases (CAs, EC 4.2.1.1) are metalloenzymes which catalyze the hydration of carbon dioxide to bicarbonate and protons. Many pathogenic bacteria encode such enzymes belonging to the α-, β-, and/or γ-CA families. In the last decade, the α-CAs from Neisseria spp. and Helicobacter pylori as...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Research Foundation
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132667/ https://www.ncbi.nlm.nih.gov/pubmed/21779249 http://dx.doi.org/10.3389/fphar.2011.00034 |