mRNA Levels in Control Rat Liver Display Strain-Specific, Hereditary, and AHR-Dependent Components

Rat is a major model organism in toxicogenomics and pharmacogenomics. Hepatic mRNA profiles after treatment with xenobiotic chemicals are used to predict and understand drug toxicity and mechanisms. Surprisingly, neither inter- and intra-strain variability of mRNA abundances in control rats nor the...

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Detalles Bibliográficos
Autores principales: Boutros, Paul C., Moffat, Ivy D., Okey, Allan B., Pohjanvirta, Raimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132743/
https://www.ncbi.nlm.nih.gov/pubmed/21760882
http://dx.doi.org/10.1371/journal.pone.0018337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132743/
https://www.ncbi.nlm.nih.gov/pubmed/21760882
http://dx.doi.org/10.1371/journal.pone.0018337

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