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mRNA Levels in Control Rat Liver Display Strain-Specific, Hereditary, and AHR-Dependent Components
Rat is a major model organism in toxicogenomics and pharmacogenomics. Hepatic mRNA profiles after treatment with xenobiotic chemicals are used to predict and understand drug toxicity and mechanisms. Surprisingly, neither inter- and intra-strain variability of mRNA abundances in control rats nor the...
Autores principales: | Boutros, Paul C., Moffat, Ivy D., Okey, Allan B., Pohjanvirta, Raimo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132743/ https://www.ncbi.nlm.nih.gov/pubmed/21760882 http://dx.doi.org/10.1371/journal.pone.0018337 |
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