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[PSI(+)] Maintenance Is Dependent on the Composition, Not Primary Sequence, of the Oligopeptide Repeat Domain

[PSI(+)], the prion form of the yeast Sup35 protein, results from the structural conversion of Sup35 from a soluble form into an infectious amyloid form. The infectivity of prions is thought to result from chaperone-dependent fiber cleavage that breaks large prion fibers into smaller, inheritable pr...

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Detalles Bibliográficos
Autores principales: Toombs, James A., Liss, Nathan M., Cobble, Kacy R., Ben-Musa, Zobaida, Ross, Eric D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132755/
https://www.ncbi.nlm.nih.gov/pubmed/21760933
http://dx.doi.org/10.1371/journal.pone.0021953