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[PSI(+)] Maintenance Is Dependent on the Composition, Not Primary Sequence, of the Oligopeptide Repeat Domain
[PSI(+)], the prion form of the yeast Sup35 protein, results from the structural conversion of Sup35 from a soluble form into an infectious amyloid form. The infectivity of prions is thought to result from chaperone-dependent fiber cleavage that breaks large prion fibers into smaller, inheritable pr...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132755/ https://www.ncbi.nlm.nih.gov/pubmed/21760933 http://dx.doi.org/10.1371/journal.pone.0021953 |