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TRIF Is a Critical Negative Regulator of TLR Agonist Mediated Activation of Dendritic Cells In Vivo

Despite recent advances in developing and licensing adjuvants, there is a great need for more potent formulations to enhance immunogenicity of vaccines. An Eimeria tenella derived antigen (rEA) augments immune responses against several pathogens in animal models and recently was confirmed to be safe...

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Detalles Bibliográficos
Autores principales: Seregin, Sergey S., Aldhamen, Yasser A., Appledorn, Daniel M., Aylsworth, Charles F., Godbehere, Sarah, Liu, Chyong-Jy Joyce, Quiroga, Dionisia, Amalfitano, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132756/
https://www.ncbi.nlm.nih.gov/pubmed/21760953
http://dx.doi.org/10.1371/journal.pone.0022064