Cargando…
TRIF Is a Critical Negative Regulator of TLR Agonist Mediated Activation of Dendritic Cells In Vivo
Despite recent advances in developing and licensing adjuvants, there is a great need for more potent formulations to enhance immunogenicity of vaccines. An Eimeria tenella derived antigen (rEA) augments immune responses against several pathogens in animal models and recently was confirmed to be safe...
Autores principales: | Seregin, Sergey S., Aldhamen, Yasser A., Appledorn, Daniel M., Aylsworth, Charles F., Godbehere, Sarah, Liu, Chyong-Jy Joyce, Quiroga, Dionisia, Amalfitano, Andrea |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132756/ https://www.ncbi.nlm.nih.gov/pubmed/21760953 http://dx.doi.org/10.1371/journal.pone.0022064 |
Ejemplares similares
-
A New Adenovirus Based Vaccine Vector Expressing an Eimeria tenella Derived TLR Agonist Improves Cellular Immune Responses to an Antigenic Target
por: Appledorn, Daniel M., et al.
Publicado: (2010) -
Vaccine Platforms Combining Circumsporozoite Protein and Potent Immune Modulators, rEA or EAT-2, Paradoxically Result in Opposing Immune Responses
por: Schuldt, Nathaniel J., et al.
Publicado: (2011) -
CR1/2 is an important suppressor of Adenovirus induced innate immune responses and is required for induction of neutralizing antibodies
por: Seregin, Sergey S., et al.
Publicado: (2009) -
Endoplasmic Reticulum Aminopeptidase-1 Functions Regulate Key Aspects of the Innate Immune Response
por: Aldhamen, Yasser A., et al.
Publicado: (2013) -
Immunogenicity when utilizing adenovirus serotype 4 and 5 vaccines expressing circumsporozoite protein in naïve and Adenovirus (Ad5) immune mice
por: Schuldt, Nathaniel J, et al.
Publicado: (2012)