Effect of Administration of Moxifloxacin plus Rifampin against Mycobacterium tuberculosis for 7 of 7 Days versus 5 of 7 Days in an In Vitro Pharmacodynamic System

Some trials administered antituberculosis agents for 5 of 7 days (5/7-day regimen) to optimize adherence. Since moxifloxacin has a longer half-life than rifampin, rifampin concentrations are <1% of the maximum concentration in serum (C(max)) on day 6 and nondetectable on day 7, while concentratio...

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Detalles Bibliográficos
Autores principales: Drusano, G. L., Sgambati, N., Eichas, A., Brown, D., Kulawy, R., Louie, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132875/
https://www.ncbi.nlm.nih.gov/pubmed/21750119
http://dx.doi.org/10.1128/mBio.00108-11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132875/
https://www.ncbi.nlm.nih.gov/pubmed/21750119
http://dx.doi.org/10.1128/mBio.00108-11

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