Insulin Receptor Substrate 2 Expression and Involvement in Neuronal Insulin Resistance in Diabetic Neuropathy

Insulin signaling depends on tyrosine phosphorylation of insulin receptor substrates (IRSs) to mediate downstream effects; however, elevated serine phosphorylation of IRS impairs insulin signaling. Here, we investigated IRS protein expression patterns in dorsal root ganglia (DRG) of mice and whether...

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Detalles Bibliográficos
Autores principales: Grote, C. W., Morris, J. K., Ryals, J. M., Geiger, P. C., Wright, D. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132877/
https://www.ncbi.nlm.nih.gov/pubmed/21754917
http://dx.doi.org/10.1155/2011/212571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132877/
https://www.ncbi.nlm.nih.gov/pubmed/21754917
http://dx.doi.org/10.1155/2011/212571

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