Cargando…
Simulation of Chaperonin Effect on Protein Folding: A Shift from Nucleation–Condensation to Framework Mechanism
[Image: see text] The iterative annealing mechanism (IAM) of chaperonin-assisted protein folding is explored in a framework of a well-established coarse-grained protein modeling tool, which enables the study of protein dynamics in a time-scale well beyond classical all-atom molecular mechanics. The...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2011
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132998/ https://www.ncbi.nlm.nih.gov/pubmed/21618995 http://dx.doi.org/10.1021/ja203275f |