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Genetic factors associated with patient-specific warfarin dose in ethnic Indonesians

BACKGROUND: CYP2C9 and VKORC1 are two major genetic factors associated with inter-individual variability in warfarin dose. Additionally, genes in the warfarin metabolism pathway have also been associated with dose variance. We analyzed Single Nucleotide Polymorphisms (SNPs) in these genes to identif...

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Detalles Bibliográficos
Autores principales: Suriapranata, Ivet M, Tjong, Wen Ye, Wang, Tingliang, Utama, Andi, Raharjo, Sunu B, Yuniadi, Yoga, Tai, Susan SW
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133537/
https://www.ncbi.nlm.nih.gov/pubmed/21639946
http://dx.doi.org/10.1186/1471-2350-12-80