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High copy arrays containing a sequence upstream of mec-3 alter cell migration and axonal morphology in C. elegans

BACKGROUND: The Caenorhabditis elegans gene mec-3 encodes a LIM-homeodomain protein that is a master regulator of touch receptor neuron genes. Two of the touch neurons, the ALM neurons, are generated in the anterior of the animal and then migrate to near the middle of the animal. In animals transfor...

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Detalles Bibliográficos
Autores principales: Toms, Nicole, Cooper, Jennifer, Patchen, Brandi, Aamodt, Eric
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC31336/
https://www.ncbi.nlm.nih.gov/pubmed/11182881
http://dx.doi.org/10.1186/1471-213X-1-2