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Human DAZL, DAZ and BOULE genes modulate primordial germ cell and haploid gamete formation

The leading cause of infertility in men and women is quantitative and qualitative defects in human germ cell (oocyte and sperm) development. Yet, it has not been possible to examine the unique developmental genetics of human germ cell formation and differentiation due to inaccessibility of germ cell...

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Detalles Bibliográficos
Autores principales: Kee, Kehkooi, Angeles, Vanessa T, Flores, Martha, Nguyen, Ha Nam, Pera, Renee A Reijo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133736/
https://www.ncbi.nlm.nih.gov/pubmed/19865085
http://dx.doi.org/10.1038/nature08562