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Applications of Propargyl Esters of Amino Acids in Solution-Phase Peptide Synthesis

Propargyl esters are employed as effective protecting groups for the carboxyl group during solution-phase peptide synthesis. The propargyl ester groups can be introduced onto free amino acids by treating them with propargyl alcohol saturated with HCl. The reaction between propargyl groups and tetrat...

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Detalles Bibliográficos
Autores principales: Ramapanicker, Ramesh, Gupta, Rohit, Megha, Rajendran, Chandrasekaran, Srinivasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133797/
https://www.ncbi.nlm.nih.gov/pubmed/21760822
http://dx.doi.org/10.1155/2011/854952