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Glycosidic enzymes enhance retinal transduction following intravitreal delivery of AAV2

PURPOSE: To determine whether the co-injection of extracellular matrix degrading enzymes improves retinal transduction following intravitreal delivery of adeno-associated virus-2 (AAV2). METHODS: AAV2 containing cDNA encoding enhanced green fluorescent protein (GFP), under the control of a chicken β...

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Detalles Bibliográficos
Autores principales: Cehajic-Kapetanovic, Jasmina, Le Goff, Magali M., Allen, Annette, Lucas, Robert J., Bishop, Paul N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133842/
https://www.ncbi.nlm.nih.gov/pubmed/21750604