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Diverse mechanisms for activation of Wnt signalling in the ovarian tumour microenvironment
Wnt signalling pathways have been shown to play key roles in both normal development and tumorigenesis. Progression of many human cancers is associated with defined mutations in Wnt pathway components that result in dysregulated β-catenin-mediated gene transcription. Although Wnt pathway mutations a...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Portland Press Ltd.
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133882/ https://www.ncbi.nlm.nih.gov/pubmed/21668411 http://dx.doi.org/10.1042/BJ20110112 |