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Quantitative Proteomic Analysis of Chromatin Reveals that Ctf18 Acts in the DNA Replication Checkpoint

Yeast cells lacking Ctf18, the major subunit of an alternative Replication Factor C complex, have multiple problems with genome stability. To understand the in vivo function of the Ctf18 complex, we analyzed chromatin composition in a ctf18Δ mutant using the quantitative proteomic technique of stabl...

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Detalles Bibliográficos
Autores principales: Kubota, Takashi, Hiraga, Shin-ichiro, Yamada, Kayo, Lamond, Angus I., Donaldson, Anne D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134068/
https://www.ncbi.nlm.nih.gov/pubmed/21505101
http://dx.doi.org/10.1074/mcp.M110.005561