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Predominant RET Germline Mutations in Exons 10, 11, and 16 in Iranian Patients with Hereditary Medullary Thyroid Carcinoma

Medullary thyroid carcinoma occurs in both sporadic (75%) and hereditary (25%) forms. The missense mutations of RET proto-oncogene in MTC development have been well demonstrated. To investigate the spectrum of predominant RET germline mutations in exons 10, 11, and 16 in hereditary MTC in Iranian po...

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Detalles Bibliográficos
Autores principales: Hedayati, Mehdi, Zarif Yeganeh, Marjan, Sheikhol Eslami, Sara, Rezghi Barez, Shekoofe, Hoghooghi Rad, Laleh, Azizi, Fereidoun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134203/
https://www.ncbi.nlm.nih.gov/pubmed/21765987
http://dx.doi.org/10.4061/2011/264248