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Evaluation of Plaque Stability of Advanced Atherosclerotic Lesions in Apo E-Deficient Mice after Treatment with the Oral Factor Xa Inhibitor Rivaroxaban

Aim. Thrombin not only plays a central role in thrombus formation and platelet activation, but also in induction of inflammatory processes. Activated factor X (FXa) is traditionally known as an important player in the coagulation cascade responsible for thrombin generation. We assessed the hypothesi...

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Detalles Bibliográficos
Autores principales: Zhou, Qianxing, Bea, Florian, Preusch, Michael, Wang, Hongjie, Isermann, Berend, Shahzad, Khurrum, Katus, Hugo A., Blessing, Erwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134269/
https://www.ncbi.nlm.nih.gov/pubmed/21772662
http://dx.doi.org/10.1155/2011/432080