Cargando…

Evaluation of Plaque Stability of Advanced Atherosclerotic Lesions in Apo E-Deficient Mice after Treatment with the Oral Factor Xa Inhibitor Rivaroxaban

Aim. Thrombin not only plays a central role in thrombus formation and platelet activation, but also in induction of inflammatory processes. Activated factor X (FXa) is traditionally known as an important player in the coagulation cascade responsible for thrombin generation. We assessed the hypothesi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Qianxing, Bea, Florian, Preusch, Michael, Wang, Hongjie, Isermann, Berend, Shahzad, Khurrum, Katus, Hugo A., Blessing, Erwin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134269/ https://www.ncbi.nlm.nih.gov/pubmed/21772662 http://dx.doi.org/10.1155/2011/432080

Ejemplares similares

Ticagrelor promotes atherosclerotic plaque stability in a mouse model of advanced atherosclerosis
por: Preusch, Michael R, et al.
Publicado: (2016)

Combined treatment with olmesartan medoxomil and amlodipine besylate attenuates atherosclerotic lesion progression in a model of advanced atherosclerosis
por: Sievers, Philipp, et al.
Publicado: (2015)

Rhizoma Coptidis Inhibits LPS-Induced MCP-1/CCL2 Production in Murine Macrophages via an AP-1 and NFκB-Dependent Pathway
por: Remppis, Andrew, et al.
Publicado: (2010)

GDF-15 protects from macrophage accumulation in a mousemodel of advanced atherosclerosis
por: Preusch, Michael R, et al.
Publicado: (2013)

AnxA5 reduces plaque inflammation of advanced atherosclerotic lesions in apoE(−/−) mice
por: Burgmaier, Mathias, et al.
Publicado: (2014)

Hypercoagulability Impairs Plaque Stability in Diabetes-Induced Atherosclerosis
por: Ambreen, Saira, et al.
Publicado: (2022)

Tryptase Promotes Atherosclerotic Plaque Haemorrhage in ApoE-/- Mice
por: Zhi, Xiuling, et al.
Publicado: (2013)

Overexpression of TGF-ß1 in Macrophages Reduces and Stabilizes Atherosclerotic Plaques in ApoE-Deficient Mice
por: Reifenberg, Kurt, et al.
Publicado: (2012)

Thrombosis and Inflammation—A Dynamic Interplay and the Role of Glycosaminoglycans and Activated Protein C
por: Kohli, Shrey, et al.
Publicado: (2022)

Dabigatran etexilate retards the initiation and progression of atherosclerotic lesions and inhibits the expression of oncostatin M in apolipoprotein E-deficient mice
por: Preusch, Michael R, et al.
Publicado: (2015)

Effects of the factor Xa inhibitor rivaroxaban on the differentiation of endothelial progenitor cells
por: Sohma, Ryoichi, et al.
Publicado: (2023)

Dystrophin deficiency reduces atherosclerotic plaque development in ApoE-null mice
por: Shami, Annelie, et al.
Publicado: (2015)

Berberine derivatives reduce atherosclerotic plaque size and vulnerability in apoE(−/−) mice
por: Chen, Junwen, et al.
Publicado: (2014)

Capsanthin Inhibits Atherosclerotic Plaque Formation and Vascular Inflammation in ApoE(−/−) Mice
por: Kim, Sungmin, et al.
Publicado: (2022)

Rivaroxaban, a Direct Oral Factor Xa Inhibitor, Attenuates Atherosclerosis by Alleviating Factor Xa–PAR2-Mediated Autophagy Suppression
por: Ito, Yusuke, et al.
Publicado: (2021)

Neonatal Subcutaneous BCG Vaccination Decreases Atherosclerotic Plaque Number and Plaque Macrophage Content in ApoE(−/−) Mice
por: Bekkering, Siroon, et al.
Publicado: (2022)

Anti-factor Xa Monitoring and Activated Charcoal for a Pediatric Patient With Rivaroxaban Overdose
por: Carr, Brendan M., et al.
Publicado: (2018)

Uptake of (68)gallium in atherosclerotic plaques in LDLR(-/-)ApoB(100/100 )mice
por: Silvola, Johanna MU, et al.
Publicado: (2011)

MicroRNA-33 Deficiency Reduces the Progression of Atherosclerotic Plaque in ApoE(−/−) Mice
por: Horie, Takahiro, et al.
Publicado: (2012)

Caspase-3 Deletion Promotes Necrosis in Atherosclerotic Plaques of ApoE Knockout Mice
por: Grootaert, Mandy O. J., et al.
Publicado: (2016)

Cordycepin stimulates autophagy in macrophages and prevents atherosclerotic plaque formation in ApoE(-/-) mice
por: Li, Xin, et al.
Publicado: (2017)

Myeloid cell-specific Irf5 deficiency stabilizes atherosclerotic plaques in Apoe(–/–) mice
por: Leipner, Julia, et al.
Publicado: (2021)

Adventitial inflammation and its interaction with intimal atherosclerotic lesions
por: Akhavanpoor, Mohammadreza, et al.
Publicado: (2014)

Determination of rivaroxaban by different factor Xa specific chromogenic substrate assays: reduction of interassay variability
por: Harenberg, Job, et al.
Publicado: (2011)

Factor Xa inhibition by rivaroxaban in the trough steady state can significantly reduce thrombin generation
por: Horinaka, Shigeo, et al.
Publicado: (2017)

DOACs in Valvular Heart Disease: Latest Key Updates on PROACT Xa (Apixaban) and INVICTUS (Rivaroxaban)
por: Ryu, Rachel
Publicado: (2022)

How radiation influences atherosclerotic plaque development: a biophysical approach in ApoE ¯/¯ mice
por: Kloosterman, Astrid, et al.
Publicado: (2017)

Phagocytosis of polymeric nanoparticles aided activation of macrophages to increase atherosclerotic plaques in ApoE(−/−) mice
por: Yin, Tieying, et al.
Publicado: (2021)

GARP and GARP-Treated tDC Prevented the Formation of Atherosclerotic Plaques in ApoE(−/-) Mice
por: Cai, Yifan, et al.
Publicado: (2021)

Extracranial carotid artery atherosclerotic plaque and APOE polymorphisms: a systematic review and meta-analysis
por: Culleton, Sinéad, et al.
Publicado: (2023)

Increased atherosclerotic plaque in AOC3 knock-out in ApoE(−/−) mice and characterization of AOC3 in atherosclerotic human coronary arteries
por: Filip, Anna, et al.
Publicado: (2022)

Rivaroxaban – an oral, direct Factor Xa inhibitor – lessons from a broad clinical study programme
por: Haas, Sylvia
Publicado: (2009)

Rivaroxaban, a factor Xa inhibitor, improves neovascularization in the ischemic hindlimb of streptozotocin-induced diabetic mice
por: Wu, Tao-Cheng, et al.
Publicado: (2015)

Factor Xa Inhibitory Profile of Apixaban, Betrixaban, Edoxaban, and Rivaroxaban Does Not Fully Reflect Their Biologic Spectrum
por: Siddiqui, Fakiha, et al.
Publicado: (2019)

Apixaban and rivaroxaban anti-Xa level utilization and associated bleeding events within an academic health system
por: Jakowenko, Nicholas, et al.
Publicado: (2020)

Rivaroxaban‐calibrated chromogenic anti‐Xa assay in cirrhosis: Use to rule out disseminated intravascular coagulation
por: Lucas, Fabienne, et al.
Publicado: (2021)

The Complementary Effects of Atorvastatin and Exercise Treatment on the Composition and Stability of the Atherosclerotic Plaques in ApoE Knockout Mice
por: Moustardas, Petros, et al.
Publicado: (2014)

Rosiglitazone modulates collagen deposition and metabolism in atherosclerotic plaques of fat-fed ApoE-knockout mice
por: ZHOU, MINGXUE, et al.
Publicado: (2015)

Tacrolimus reduces atherosclerotic plaque formation in ApoE(−/−) mice by inhibiting NLRP3 inflammatory corpuscles
por: Li, Xiao, et al.
Publicado: (2020)

Interventional hepatic apoC-III knockdown improves atherosclerotic plaque stability and remodeling by triglyceride lowering
por: Ramms, Bastian, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_q6mavua3mu5t9a6a1mbko4flpc