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EGF and TGF-β1 Effects on Thyroid Function

Normal epithelial thyroid cells in culture are inhibited by TGF-β1. Instead, transformed thyroid cell lines are frequently resistant to its growth inhibitory effect. Loss of TGF-β responsiveness could be due to a reduced expression of TGF-β receptors, as shown in transformed rat thyroid cell lines a...

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Detalles Bibliográficos
Autores principales: Mincione, Gabriella, Di Marcantonio, Maria Carmela, Tarantelli, Chiara, D'Inzeo, Sonia, Nicolussi, Arianna, Nardi, Francesco, Donini, Caterina Francesca, Coppa, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134325/
https://www.ncbi.nlm.nih.gov/pubmed/21760980
http://dx.doi.org/10.4061/2011/431718