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Hypoxia-Inducible Factor in Thyroid Carcinoma

Intratumoural hypoxia (low oxygen tension) is associated with aggressive disease and poor prognosis. Hypoxia-inducible factor-1 is a transcription factor activated by hypoxia that regulates the expression of genes that promote tumour cell survival, progression, metastasis, and resistance to chemo/ra...

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Detalles Bibliográficos
Autores principales: Burrows, Natalie, Babur, Muhammad, Resch, Julia, Williams, Kaye J., Brabant, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134378/
https://www.ncbi.nlm.nih.gov/pubmed/21765994
http://dx.doi.org/10.4061/2011/762905