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Genistein inhibits proliferation of colon cancer cells by attenuating a negative effect of epidermal growth factor on tumor suppressor FOXO3 activity

BACKGROUND: Soy consumption is associated with a lower incidence of colon cancer which is believed to be mediated by one of its of components, genistein. Genistein may inhibit cancer progression by inducing apoptosis or inhibiting proliferation, but mechanisms are not well understood. Epidermal grow...

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Detalles Bibliográficos
Autores principales: Qi, Wentao, Weber, Christopher R, Wasland, Kaarin, Savkovic, Suzana D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134425/
https://www.ncbi.nlm.nih.gov/pubmed/21639915
http://dx.doi.org/10.1186/1471-2407-11-219