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Genistein inhibits proliferation of colon cancer cells by attenuating a negative effect of epidermal growth factor on tumor suppressor FOXO3 activity
BACKGROUND: Soy consumption is associated with a lower incidence of colon cancer which is believed to be mediated by one of its of components, genistein. Genistein may inhibit cancer progression by inducing apoptosis or inhibiting proliferation, but mechanisms are not well understood. Epidermal grow...
Autores principales: | Qi, Wentao, Weber, Christopher R, Wasland, Kaarin, Savkovic, Suzana D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134425/ https://www.ncbi.nlm.nih.gov/pubmed/21639915 http://dx.doi.org/10.1186/1471-2407-11-219 |
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