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Evidence That Lipopolisaccharide May Contribute to the Cytokine Storm and Cellular Activation in Patients with Visceral Leishmaniasis

BACKGROUND: Visceral leishmaniasis (VL) is characterized by parasite-specific immunosuppression besides an intense pro-inflammatory response. Lipopolisaccharide (LPS) has been implicated in the immune activation of T-cell deficient diseases such as HIV/AIDS and idiopathic lymphocytopenia. The source...

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Detalles Bibliográficos
Autores principales: Santos-Oliveira, Joanna R., Regis, Eduardo G., Leal, Cássia R. B., Cunha, Rivaldo V., Bozza, Patrícia T., Da-Cruz, Alda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134430/
https://www.ncbi.nlm.nih.gov/pubmed/21765960
http://dx.doi.org/10.1371/journal.pntd.0001198