Bioinformatic and Genetic Association Analysis of MicroRNA Target Sites in One-Carbon Metabolism Genes

One-carbon metabolism (OCM) is linked to DNA synthesis and methylation, amino acid metabolism and cell proliferation. OCM dysfunction has been associated with increased risk for various diseases, including cancer and neural tube defects. MicroRNAs (miRNAs) are ∼22 nt RNA regulators that have been im...

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Detalles Bibliográficos
Autores principales: Stone, Nicole, Pangilinan, Faith, Molloy, Anne M., Shane, Barry, Scott, John M., Ueland, Per Magne, Mills, James L., Kirke, Peader N., Sethupathy, Praveen, Brody, Lawrence C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134459/
https://www.ncbi.nlm.nih.gov/pubmed/21765920
http://dx.doi.org/10.1371/journal.pone.0021851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134459/
https://www.ncbi.nlm.nih.gov/pubmed/21765920
http://dx.doi.org/10.1371/journal.pone.0021851

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