Developing Single-Molecule TPM Experiments for Direct Observation of Successful RecA-Mediated Strand Exchange Reaction

RecA recombinases play a central role in homologous recombination. Once assembled on single-stranded (ss) DNA, RecA nucleoprotein filaments mediate the pairing of homologous DNA sequences and strand exchange processes. We have designed two experiments based on tethered particle motion (TPM) to inves...

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Detalles Bibliográficos
Autores principales: Fan, Hsiu-Fang, Cox, Michael M., Li, Hung-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134461/
https://www.ncbi.nlm.nih.gov/pubmed/21765895
http://dx.doi.org/10.1371/journal.pone.0021359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134461/
https://www.ncbi.nlm.nih.gov/pubmed/21765895
http://dx.doi.org/10.1371/journal.pone.0021359

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