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HIV-2 Integrase Variation in Integrase Inhibitor-Naïve Adults in Senegal, West Africa

BACKGROUND: Antiretroviral therapy for HIV-2 infection is hampered by intrinsic resistance to many of the drugs used to treat HIV-1. Limited studies suggest that the integrase inhibitors (INIs) raltegravir and elvitegravir have potent activity against HIV-2 in culture and in infected patients. There...

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Detalles Bibliográficos
Autores principales: Gottlieb, Geoffrey S., Smith, Robert A., Dia Badiane, Ndeye Mery, Ba, Selly, Hawes, Stephen E., Toure, Macoumba, Starling, Alison K., Traore, Fatou, Sall, Fatima, Cherne, Stephen L., Stern, Joshua, Wong, Kim G., Lu, Paul, Kim, Moon, Raugi, Dana N., Lam, Airin, Mullins, James I., Kiviat, Nancy B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134476/
https://www.ncbi.nlm.nih.gov/pubmed/21765953
http://dx.doi.org/10.1371/journal.pone.0022204