Interaction networks of lithium and valproate molecular targets reveal a striking enrichment of apoptosis functional clusters and neurotrophin signaling

The overall neurobiological mechanisms by which lithium and valproate stabilize mood in bipolar disorder patients have yet to be fully defined. The therapeutic efficacy and dissimilar chemical structures of these medications suggest that they perturb both shared and disparate cellular processes. To...

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Detalles Bibliográficos
Autores principales: Gupta, Ajay, Schulze, Thomas G, Nagarajan, Vijayaraj, Akula, Nirmala, Corona, Winston, Jiang, Xue-ying, Hunter, Natasha, McMahon, Francis J, Detera-Wadleigh, Sevilla D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134562/
https://www.ncbi.nlm.nih.gov/pubmed/21383773
http://dx.doi.org/10.1038/tpj.2011.9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134562/
https://www.ncbi.nlm.nih.gov/pubmed/21383773
http://dx.doi.org/10.1038/tpj.2011.9

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