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PATHWAY BASED ANALYSIS OF GENOTYPES IN RELATION TO ALCOHOL DEPENDENCE

We introduce a method for detecting variants in several genes of related function with small effect on a phenotype of interest. Our method uses logistic regression to test whether multiple alleles within a functional set have significantly higher than expected predictive value, even though none indi...

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Detalles Bibliográficos
Autores principales: Reimers, Mark A, Riley, Brien P, Kalsi, Gursharan, Kertes, Darlene A, Kendler, Kenneth S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134610/
https://www.ncbi.nlm.nih.gov/pubmed/21468025
http://dx.doi.org/10.1038/tpj.2011.10