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PATHWAY BASED ANALYSIS OF GENOTYPES IN RELATION TO ALCOHOL DEPENDENCE
We introduce a method for detecting variants in several genes of related function with small effect on a phenotype of interest. Our method uses logistic regression to test whether multiple alleles within a functional set have significantly higher than expected predictive value, even though none indi...
Autores principales: | Reimers, Mark A, Riley, Brien P, Kalsi, Gursharan, Kertes, Darlene A, Kendler, Kenneth S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134610/ https://www.ncbi.nlm.nih.gov/pubmed/21468025 http://dx.doi.org/10.1038/tpj.2011.10 |
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